Principal Investigator at Huaibei Normal University | China
Dr. Dayong Xu is an Associate Professor at the School of Life Sciences, Huaibei Normal University, China. He is an active researcher specializing in CRISPR technologies and molecular diagnostics. His contributions span across microbiology, biotechnology, and molecular biology, with a strong emphasis on developing innovative diagnostic tools and exploring microbial mechanisms of resistance and virulence. As a corresponding author on several high-impact publications, Dr. Xu has collaborated with distinguished researchers worldwide, advancing the field of molecular detection systems. His research outputs include pioneering CRISPR-based diagnostic platforms for viral, bacterial, and fungal pathogens, along with studies on antifungal resistance and microbial physiology. With a balance of academic scholarship and practical application, he is recognized for translating scientific knowledge into technologies with potential clinical and industrial impact. Dedicated to innovation and excellence, Dr. Xu has built a professional reputation as a leading scientist in molecular diagnostics and microbial pathogenesis.
Professional Profiles
Scopus Profile | Orcid Profile
Education
Dr. Dayong Xu pursued his academic training in the life sciences, where he cultivated expertise in molecular biology, microbiology, and biotechnology. His education provided him with a strong foundation in both theoretical knowledge and experimental skills, allowing him to investigate fundamental processes in microbial systems while applying molecular techniques to real-world challenges. Through his academic journey, he gained exposure to advanced genetic tools, protein analysis, and diagnostic development. This training equipped him to explore areas such as CRISPR-mediated detection methods and the molecular basis of antifungal drug resistance. By integrating rigorous coursework with extensive laboratory research, Dr. Xu developed the ability to connect basic science with translational applications. His educational path strengthened his interdisciplinary approach, fostering collaborations across genetics, microbiology, and biotechnology. This background has been essential in enabling him to address complex research questions and contribute meaningfully to both academic science and applied diagnostic innovation.
Experience
Dr. Dayong Xu has accumulated significant academic and research experience as an Associate Professor at Huaibei Normal University. His role involves a combination of teaching, mentoring, and leading innovative scientific investigations in molecular diagnostics and microbiology. He has published extensively in peer-reviewed journals, often serving as a corresponding author, which reflects his leadership in collaborative projects. His experience spans the design and optimization of CRISPR-based diagnostic systems, the study of antifungal resistance in Candida albicans, and the development of microbial fermentation strategies for bioactive compounds. He has also explored genetic pathways involved in microbial virulence, calcium homeostasis, and stress tolerance, contributing to a deeper understanding of pathogen biology. Beyond research, Dr. Xu engages in academic guidance for students and fosters collaborations with international scientists. His extensive experience highlights his ability to integrate laboratory research, academic leadership, and practical innovation in advancing molecular and microbial sciences.
Research Focus
Dr. Dayong Xu’s research is centered on CRISPR technology, molecular diagnostics, and microbial pathogenesis. He is particularly focused on designing and optimizing CRISPR/Cas-based platforms for the rapid and accurate detection of pathogens, including viruses, bacteria, and fungi. His studies extend to the molecular mechanisms underlying antifungal resistance in Candida albicans, where he investigates genetic interactions, membrane transport proteins, and signaling pathways that affect drug tolerance and virulence. He also explores microbial enzyme functions, protein expression, and biotechnological applications, such as the transformation of biochemical compounds and the fermentation-based production of antimicrobial agents. His research integrates basic molecular biology with translational outcomes, bridging the gap between laboratory innovation and real-world diagnostic needs. With a strong emphasis on precision and applicability, Dr. Xu aims to contribute to global health by advancing tools for early disease detection, therapeutic development, and microbial understanding through cutting-edge molecular approaches.
Publication Top Notes
Title: Efficient Synthesis of Tetrahydroisoquinoline Alkaloids from Dopamine and Natural Phenolic Acids by Whole-Cell Biocatalysis
Journal: ACS Sustainable Chemistry and Engineering, 2025
Summary: This article presents a sustainable biocatalytic approach for synthesizing tetrahydroisoquinoline alkaloids using dopamine and natural phenolic acids as substrates. Whole-cell systems are employed to achieve efficient synthesis, highlighting green chemistry applications in natural product production.
Title: Fast-Flu: RT-RPA-CRISPR/Cas12a assisted one-step platform for rapid influenza B virus detection
Journal: Microbiology Spectrum, 2025
Summary: The study introduces a rapid diagnostic platform, Fast-Flu, combining RT-RPA with CRISPR/Cas12a in a single step to detect influenza B virus. The method is highly sensitive, specific, and time-efficient, offering potential for point-of-care influenza diagnostics.
Title: Heterologous Expression and Enzymatic Properties of β-Glucuronidase from Clostridium perfringens and Its Application in Bilirubin Transformation
Journal: Microorganisms, 2025
Summary: This research reports the heterologous expression and characterization of β-glucuronidase from Clostridium perfringens. The enzyme’s biochemical properties are examined, and its application in bilirubin transformation is demonstrated, providing insights into microbial enzyme utilization in biomedicine.
Conclusion
Dr. Dayong Xu exemplifies the role of a modern life sciences researcher who integrates deep biological knowledge with technological innovation. His career reflects a commitment to both academic scholarship and applied solutions, particularly in the fields of CRISPR diagnostics and microbial pathogenesis. By combining his expertise in molecular biology with his leadership in collaborative research, he has contributed to advancing scientific understanding and developing diagnostic systems with significant potential for clinical use. His publications, many of which list him as a corresponding author, showcase his influence in driving forward high-impact research. Beyond his scientific achievements, Dr. Xu is dedicated to mentoring young researchers and fostering international collaborations that broaden the reach of his work. Through a balance of innovation, research, and education, he continues to play an influential role in shaping the future of molecular diagnostics, microbial biology, and applied biotechnology.