Prof. Dr. Hans Rudolf Pfaendler is a distinguished researcher and faculty member at Ludwig-Maximilians-Universität München, Germany, with a focus on microbiology and chemical sciences. Over his career, he has authored 35 publications that have collectively garnered 660 citations, reflecting both the quality and impact of his work. His research spans innovative methodologies in microbiology, including the development of the CarbaLux test for detecting carbapenemases and AmpC beta-lactamases, as well as contributions to organic chemistry, such as novel formaldehyde derivatives and vicinal diamination of terminal olefins. Pfaendler has collaborated with a broad network of 46 co-authors, highlighting his commitment to interdisciplinary and international research initiatives. His work has significantly advanced diagnostic techniques and synthetic chemistry, providing tools that are not only academically influential but also societally relevant, particularly in addressing antimicrobial resistance and chemical synthesis challenges. Recognized for both methodological innovation and practical applications, his scholarship bridges fundamental research and translational impact, underlining his standing as a leading figure in his field.
Profiles: Scopus | ORCID
Featured Publications
1. Pfaendler, H. R. (1994). ß-Lactame – ein aktueller Überblick: The Organic Chemistry of β-Lactams. Von G. I. Georg. VCH, Weinheim 1993. 381 S., 39 Abb., 68 Tab., geb., DM 189,-. ISBN 3-527-28188-6. Nachrichten aus Chemie, Technik und Laboratorium, 42(1), 29–30.Pf.
2. Pfaendler, H. R., Hendel, W., & Nagel, U. (1992). Stable Oxapenem-3-Carboxylic Acids – A New Class of β-Lactam Antibiotics. Influence of 2- and 6-Alkyl Substituents. Zeitschrift für Naturforschung B, 47(7–8), 726–732
3. Pfaendler, H., Hartung, R., Golz, G., Schlaf, S., Silvennoinen, G., Polborn, K., & Mayer, P. (2009). A Simple and Efficient Preparation of Novel Formaldehyde Derivatives. Synthesis, 2009(1), 9–16.
4. Pfaendler, H. R. (1990). Robinsonade: „Robert Robinson ‐ Chemist Extraordinary”. Von Trevor I. Williams. Oxford University Press (Clarendon Press Oxford) 1990. 201 S., 13 Fotos, geb. $ 25.00, ISBN 0‐19‐858180‐7. Nachrichten aus Chemie, Technik und Laboratorium, 38(10), 318–319.
5. Pfaendler, H. R., Weishaupt, R., & Meffert, H. (2000). Synthesis and Biological Activities of an α-Methyl and a β-Methyl Carbapenem and the Corresponding Unsubstituted Compound. Bioorganic & Medicinal Chemistry Letters, 10(12), 1417–1420.
Prof. Dr. Hans Rudolf Pfaendler’s work advances the rapid detection and characterization of antimicrobial resistance through innovative diagnostic tools, such as the CarbaLux test for carbapenemases and AmpC beta-lactamases. By enabling faster, more accurate identification of resistant bacterial strains, his research supports improved clinical decision-making, enhances patient outcomes, and informs global strategies to combat antibiotic resistance. This contribution bridges fundamental microbiology with practical healthcare applications, promoting both scientific understanding and societal impact.