Professor | Centro de Investigación en Sanidad Animal (CISA)-CSIC | Spain
Prof. Dr. Noemí Sevilla Hidalgo is a distinguished Full Professor and Director at the Centro de Investigación en Sanidad Animal (CISA-INIA, CSIC, Spain), with a prolific career spanning over three decades in virology, immunology, and animal health, focusing on zoonotic and veterinary pathogens. Her research has elucidated viral immune evasion strategies, host-pathogen interactions, and immune responses in both small and large animal models, directly informing vaccine design. After completing her PhD in Molecular Biology at Universidad Autónoma de Madrid, where she received the Doctorate Extraordinary Award, she pursued postdoctoral training at The Scripps Research Institute (TSRI, USA) under a Human Frontiers Fellowship, studying dendritic cell roles in viral immunity and demonstrating dual viral evasion mechanisms. These results were published in high-impact journals and have received over 3,115 citations. Returning to Spain via the Ramon y Cajal program, she established her research group at CISA, focusing on Bluetongue virus (BTV), Peste des Petits Ruminants virus (PPRV), and more recently, SARS-CoV-2 and Crimean-Congo hemorrhagic fever virus. Her contributions span viral immune evasion, characterization of host immune responses to BTV and PPRV, and the development of recombinant adenoviral vaccine platforms. Sevilla has actively contributed to scientific leadership through conference organization, editorial service, and grant review panels. She has received eight competitive fellowships and authored 70 publications, maintaining an h-index of 30 with 3,115 citations, reflecting her global impact and sustained contributions to virology, immunology, and vaccine research.
Profiles: Scopus | ORCID
Featured Publications
1. Louloudes-Lázaro, A., Nogales-Altozano, P., Rojas, J. M., Veloz, J., Carlón, A. B., Van Rijn, P. A., Martín, V., Fernández-Sesma, A., & Sevilla, N. (2025). Double-stranded RNA orbivirus disrupts the DNA-sensing cGAS-sting axis to prevent type I IFN induction. Cellular and Molecular Life Sciences.
2. Herder, V., Caporale, M., MacLean, O. A., Pintus, D., Huang, X., Nomikou, K., Palmalux, N., Nichols, J., Scivoli, R., Boutell, C., … (2024). Correlates of disease severity in bluetongue as a model of acute arbovirus infection. PLoS Pathogens.
3. Ciudad, C. J., Valiuska, S., Rojas, J. M., Nogales-Altozano, P., Aviñó, A., Eritja, R., Chillón, M., Sevilla, N., & Noé, V. (2024). Polypurine reverse hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection. Journal of Biological Chemistry. Cited by: 4
4. Herder, V., Caporale, M., MacLean, O. A., Pintus, D., Huang, X., Nomikou, K., Palmalux, N., Nichols, J., Scivoli, R., Boutell, C., … (2024). A machine learning framework to identify the correlates of disease severity in acute arbovirus infection [Preprint]. bioRxiv.Cited by: 4
5. Pinsino, A., & Sevilla, N. (2024). Editorial: Women in comparative immunology. Frontiers in Immunology.Cited by: 5